The treatment of super refractory status epilepticus
Super refractory status epilepticus is defined as status epilepticus that continues or recurs 24 h or more after the onset of anaesthetic therapy including those cases where status epilepticus recurs on the reduction or withdrawal of anaesthesia It is an uncommon but important clinical problem with high mortality and morbidity rates This article reviews the treatment approaches
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Super Refractory Status EpilepticusPDF Free Download
Super Refractory Status Epilepticus Mauricio Ruiz Cuero 1 Panayiotis N Varelas 1 2 # Springer Science Business Media New York 2015 Abstract Although the vast majority of patients with status epilepticus SE respond fairly well to the first or second line anti epileptics a minority require anesthetic agents to put the seizures under control
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The ketogenic diet for super refractory status epilepticus
Super refractory status epilepticus or SRSE occurs when status epilepticus persists for at least 24 hours after the initiation of anesthesia About 15 of people with SE will progress to SRSE Of those that do outcomes are quite poor up to 40 die and about 3 of every 4 survivors have a poor functional outcome at least at hospital discharge
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Progressive Brain Atrophy in Super refractory Status
Super refractory status epilepticus SRSE is defined as SE that continues or recurs 24 hours or more after the onset of anesthetic therapy 1 Mortality ranges from 30 to 50 and half of survivors have a poor functional outcome despite seizure control 2 3
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Ketamine to treat super refractory status epilepticus
Objective To test ketamine infusion efficacy in the treatment of super refractory status epilepticus SRSE we studied patients with SRSE who were treated with ketamine retrospectively We also studied the effect of high doses of ketamine on brain physiology as reflected by invasive multimodality monitoring MMM Methods We studied a consecutive series of 68 patients with SRSE
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Refractory and Super refractory Status Epilepticus
Super refractory status epilepticus is a status epilepticus that continues for ³24 hours despite anesthetic treatment or recurs on an attempted wean of the anesthetic regimen Both can occur in patients known to have epilepsy or de novo with increasing recognition of autoimmune and genetic causes Electroencephalography monitoring is
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New Onset Super Refractory Status Epilepticus Following
New Onset Super Refractory Status Epilepticus Following Fever More than a Case of NORSE Abstract We present the case of a healthy 32 year old woman who came to our hospital due to fever and left otalgia She subsequently developed dizziness and gait instability opsoclonus myoclonus syndrome and altered level of consciousness
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Status Epilepticus Refractory Status Epilepticus and
PURPOSE OF REVIEW Status epilepticus refractory status epilepticus and super refractory status epilepticus can be life threatening conditions This article presents an overview of the three conditions and discusses their management and outcomes RECENT FINDINGS Status epilepticus was previously defined as lasting for 30 minutes or longer but now is more often defined as lasting 5
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Super Refractory Status Epilepticus Prognosis and Recent
Abstract Super refractory status epilepticus SRSE is a life threatening neurological emergency with high morbidity and mortality It is defined as status epilepticus SE that continues or recurs 24 hours or more after the onset of anesthesia including those cases in which SE recurs on the reduction or withdrawal of anesthesia
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If those drugs are insufficient to control SE or SE recurs as they are withdrawn the course of treatment may become much longer and this is super refractory status epilepticus SRSE defined as SE that continues 24 h or more after the onset of anaesthetic therapy including those cases that recur on the reduction or withdrawal of anasesthesia
Get PriceThe Treatment of Super Refractory Status Epilepticus
Super refractory status epilepticus is defined as status epilepticus that continues or recurs 24 h or more after the onset of anaesthetic therapy including those cases where status epilepticus
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The word super refectory is coined recently in status epilepticus SE when the seizures continue unabated for a day or more despite rigorous management leading to subsequent neuronal injury most of the times and even death 1 The super refractory SE is a rare but not uncommon type of ongoing seizure activity and the exact pathophysiology
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PulmCrit Resuscitationist s guide to status epilepticus
The combination of these two effects causes a profound decrease in CNS activity Ketamine combined with propofol ketofol was effective in published series of patients with super refractory status epilepticus Sabharwal 2015 Hofler 2016 5 Choice of paralytic for intubation The ideal paralytic for status epilepticus is controversial
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New onset refractory status epilepticus NORSE
Super refractory status epilepticus is best managed in a neuroscience centre with access to diagnostic tools and appropriate facilities including continuous or frequent EEG monitoring neuroimmunology input or extracorporeal membrane oxygenation Early
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New onset refractory status epilepticus Genetic and Rare
New onset refractory status epilepticus NORSE occurs when a person without a previous history of seizures experiences status epilepticus SE without a clear cause SE describes a state in which a person has one prolonged seizure or a cluster of seizures without recovery time in between
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treatment of super refractory status epilepticus a
Super refractory status epilepticus is defined as status epilepticus that continues or recurs 24 h or more after the onset of anaesthetic therapy including those cases where status epilepticus recurs on the reduction or withdrawal of anaesthesia It is an uncommon
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Predictors of Outcome in Refractory Status Epilepticus
Refractory status epilepticus RSE has been defined variably in the literature as seizures that do not respond to 2 1 4 or 3 5 8 different antiepileptic medications usually intravenous benzodiazepines as a first line agent and intravenous phenytoin phenobarbital or valproic acid as a second line agent 9 Alternatively RSE has been defined by the duration of seizure activity of 1 2 or 2
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Pediatric refractory and super refractory status
Nevertheless continuous or intermittent seizures may persist for 24 h or more following the administration of general anesthesia or recur after its withdrawal The resulting condition is known as super refractory status epilepticus SRSE Identifying the underlying etiology of
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Costs length of stay and mortality of super‐refractory
Super‐refractory status epilepticus SRSE is a severe condition in which a patient in status epilepticus SE for ≥24 h does not respond to first‐ second‐ or third‐line therapy The economic impact of SRSE treatment remains unclear A health insurance research database was used for a population‐based estimation of SRSE
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Objective To provide an estimate of the annual number of super refractory status epilepticus SRSE cases in the US and to evaluate utilization of hospital resources by these patients Methods The Premier Hospital Database was utilized to estimate the number of SRSE cases based on hospital discharges during 2012
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Super refractory status epilepticus in a 29 year old
Super refractory status epilepticus SRSE is defined as status epilepticus SE that persists at least 24 h despite the administration of intravenous anesthetic drugs IVADs including those cases where SE recurs after the reduction or withdrawal of anesthesia 1 SRSE is seen in about 12 to 26 of SE cases in the general population 2 The exact prevalence among pregnant patients remains
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New onset refractory status epilepticus Genetic and Rare
The cause of status epilepticus SE can be found during initial tests in about 80 of cases The remaining cases are classified as new onset refractory status epilepticus NORSE Further more extensive testing finds a cause in about 40 of NORSE cases including autoimmune encephalitis paraneoplastic encephalitis other known inflammatory or autoimmune diseases rare genetic
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outcome of therapies in refractory and super refractory
Super refractory status epilepticus is defined as status epilepticus that continues 24 h or more after the onset of anaesthesia including those cases in which the status epilepticus recurs on the reduction or withdrawal of anaesthesia
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Refractory and Super Refractory Status Epilepticus an
drugs including a benzodiazepine The term super refractory status epilepticus was introduced during the London–Inns bruck Colloquium on status epilepticus in 2011 and refers to status epilepticus that continues or recurs 24 h or more after the initiation of treatment with anesthetic antiepileptic drugs
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Updates in Refractory Status Epilepticus
Super refractory status epilepticus SRSE is defined as SE that persists despite 24 hour treatment with IV anesthetic and recurs when weaning the patient off the anesthetic New onset refractory status epilepticus NORSE is defined as new onset RSE where no discernible cause is identifiable in otherwise healthy individuals 5 6
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Status Epilepticus Refractory Status Epilepticus and
SUMMARY Status epilepticus can be a life threatening condition associated with multiple complications including death and can progress to refractory status epilepticus and super refractory status epilepticus More studies are needed to delineate the best management of these three entities
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Status epilepticus Refractory and super refractory
Super refractory SE SRSE is defined as SE that continues for 24 hours or more after the use of anesthetic therapy including cases that recur on weaning of the anesthestic agent RSE occurs in 23 48 of the patients and SRSE in approximately 22 of the patients with SE
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Refractory and Super refractory Status Epilepticus
Super refractory status epilepticus is a status epilepticus that continues for ≥24 hours despite anesthetic treatment or recurs on an attempted wean of the anesthetic regimen Both can occur in patients known to have epilepsy or de novo with increasing recognition of autoimmune and genetic causes
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Treatment of Super Refractory Status Epilepticus A Review
Super refractory status epilepticus SRSE is defined as seizure activity greater than 24 hours despite treatment with an anesthetizing ASM 2 This includes cases in which seizures recur with an attempted withdrawal of the anesthetics 3 4
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Status epilepticus Refractory and super refractory Dubey
Super refractory status epilepticus Super refractory SE SRSE is defined as status epilepticus that continues for 24 hours or more after the use of anesthetic therapy including the cases in whom SE recurs on weaning of anesthesia It is an uncommon but important clinical problem with a
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The Treatment of Super Refractory Status Epilepticus
Super refractory status epilepticus status epilepticus that continues or recurs 24 hours or more after the onset of anesthetic therapy is a medical emergency The authors present an algorithm
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PodcastThe ketogenic diet for super refractory status
Someone who has persistent seizures that last more than 24 hours despite treatment is in super refractory status epilepticus The condition is rare but often results in death or disability Bringing someone out of status usually involves treatment with anti seizure medications and anesthetics but other therapies are beginning to gain attention
Get PriceTreatment of Super Refractory Status Epilepticus A Review
Super refractory status epilepticus SRSE is defined as seizure activity greater than 24 hours despite treatment with an anesthetizing ASM 2 This includes cases in which seizures recur with an attempted withdrawal of the anesthetics 3 4
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